Citrus aurantium (bitter orange) is a plant belonging to the family Rutaceae, The most important biologically active constituents of the C. aurantium fruits are phenethylamine alkaloids octopamine, synephrine, tyramine, N-methyltyramine and hordenine. It is rich in vitamin C, flavonoids and volatile oil. Synephrine is a primary synthesis compound with pharmacological activities such as vasoconstriction, elevation of blood pressure and relaxation of bronchial muscle. whose fruit extracts have been used for the treatment of various diseases such as gastrointestinal disorders, insomnia, head aches, cardiovascular diseases, cancer, antiseptic, anti-oxidant, antispasmodic, aromatic, astringent, carminative, digestive, sedative, stimulant, stomachic and tonic and by research novel use is found in obesity and related risks even life threatening are continuously increasing through out world in all age groups. Many marketed formulations claim to possess antiobesity actions, but still many herbs which have claims to this need to be investigated and their claims to be authenticated.