Guggul is made from the sap (gum resin) of the Commiphora mukul tree, which is native to India. This tree has been used in Ayurvedic medicine for centuries, and Ayurvedic texts dating back to 600 BC recommend it for treating atherosclerosis. It is praised for its anti-inflammatory properties. Preliminary research suggests it may help treat certain anti-inflammatory conditions, such as acne, eczema, psoriasis, and arthritis. It has also been used to promote weight loss, treat hypothyroidism, and manage cholesterol and blood sugar levels